Rising unemployment is one of the consequences of the COVID-19 pandemic in many countries. This, in turn, has forcedpolicymakers to respond immediately with policy tools to minimize unemployment. The purpose of our study is to contribute toempirical knowledge by looking at activities of 40 local government units to counteract unemployment in the cross-border regionon the Polish side. In doing this, our study contributes to the efforts to manage unemployment in times of COVID-19 and othercrisis situations. The results show that most of the rural and rural-urban communes did not undertake diagnostic activities thatwould allow one to identify the economic sectors most affected by changes related to the COVID-19 pandemic, e.g., reduction inthe number of employees, suspension, or liquidation of activities. According to LGUs surveyed, companies operating in rural-urban communes applied much more frequently for support for job protection in connection with the COVID-19 pandemic thancompanies located in rural communes.The COVID-19 pandemic demonstrated the crucial role of LGUs in overcoming its impacts. The empirical results of this study(in-depth interviews) indicate that policy makers should pay more attention to consolidating or strengthening the role of LGUs innational disaster management and provide them with the competencies and resources necessary to deal with emergencies (inparticular, they concern strengthening cooperation and coordination with other levels of government, effective communicationand sharing of good practices also in cross-border areas). It would strengthen decision support systems (DSS) in the regions.